Properties of mandelic acid
Mandelac is a line of products formulated with mandelic acid, recommended especially for those skins that have intolerance to other alpha hydroxy acids (AHAs).
Mandelic acid, also known as phenylglycollic acid, is an AHA derived from the hydrolysis of bitter almond extract. Has been commonly used to treat photo aging, irregular pigmentation, non cystic inflammatory acne and to prepare the skin in pre and post laser resurfacing.
Indications
Hemosiderotic skin pigmentation (sclerosis of varicose veins, laser
treatments, vein problems ...) and dark circles. All
skin types.
Presentation
60 ml
Properties and advantages Suitable for sensitive skin
Compared with glycolic acid, mandelic acid has a larger molecule size that makes its penetration through the stratum corneum slower, without causing irritation or itching. Chemical peeling
The chemical peeling caused from mandelic acid, compared with glycolic acid, produces a minor irritation, and is less likely to cause erythema, hot areas, scabs, blisters or other adverse effects on the epidermis. Immediate effects on the epidermis
Mandelic acid quickly improves the texture of the skin by decreasing the cohesion of the corneocytes, activating cell regeneration and promoting a thinner stratum corneum, which is more flexible and hydrated. Large capacity for dermal remodeling
Mandelic acid has a pKa of 3.41, so its ability to increase collagen synthesis, elastin and glycosaminoglycans (GAGs) in the papillary dermis is higher than other AHAs such as glycolic acid (pKa = 3.83). De-pigmentation action
Melasma, hyper pigmentation, post inflamitory and Lentigines improve with mandelic acid based products. In many cases, melasma improves up to 50% after one month of treatment with a concentration of 10%. Unlike patients with dark photo types treated with glycolic acid, hydroquinone, or tretinoin, with mandelic acid we do not observe cases of hyper pigmentation or post inflammatory. Sebum regulating, antibacterial, and anti microbe action
Chemically, mandelic acid has a structure similar to other broad spectrum antibiotics.
It Controls and normalizes the amount of fat that penetrate into the hair follicle, reduces the presence of P. acnes, improve the appearance of inflammatory skin pustules, comedones, papular acne, rosacea and folliculitis.
In addition, preparation of the skin with mandelic acid 2-4 weeks be fore and after laser resurfacing, prevents the formation of bacterial infections by Gram (-).